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Back to the drawing board - Elizabeth Unexplained
Lots of data but no answers
greyautumnrain
greyautumnrain
Back to the drawing board
I have a doctor's appointment tomorrow. Its the post mortem for IVF #1, the cycle that just failed. One thing is certain, we will be trying again. Its just that prior to the next cycle they expect us to have a chat with Jedi Master Grace Wendo.

I expect that not much time will be spent pondering the sad and untimely demise of my two embryos. If you recall, at the time I didn't want to go into what 7Bfair and 5Cfair meant. At the time these were potentially my babies, and I didn't want to say unkind things about them. Now they are dead, so we can be a little more honest. The number is the number of cells, so we had one with seven cells and one with 5. Ideally at three days post retrieval you'd want them to have eight cells. The letter rating is for fragmentation -- home much cytoplasm ends up outside the cell boundaries. A is for less than 5%, which is ideal. Lastly, we have the other rating, which is for cell symmetry. This rating can be 'good', 'fair', or 'poor'. The embryos that have a rating of 8Agood are the ones that are most likely to implant, but even then there are no guarentees. I don't think anyone is suprised that my less than perfect embryos didn't make it. Disappointed certainly, but not surprised.

What I want to know is why the heck didn't I produce more eggs? Six mature eggs is not a great result. Sure, we would have only transferred two embryos anyway, but having more to choose from would have increased our odds. To be brutally frank about my poor little embryos, I doubt that the 5Cfair one would have made the cut if we'd had more embryos to work with, unless we just tossed it in there for the heck of it, knowing its chances were very slim. To put it in ballroom terms, it made the final because we didn't have enough competitors to run the event as a semi-final. So I want more eggs next time because more eggs means a better chance at more embryos which means we can pick the ones with the best chance of actually making it, which will hopefully mean a better chance for success. I have no idea why I didn't make more eggs since ovulation has never been a problem for me, but I suspect its because my ovaries are as bloody-minded as the rest of me and resent being prodded to deviate from their intended path.

So, tomorrow the chat and the questions. Then hopefully supression starting in mid to late January, followed by stimming in mid to late February, and retrival and transfer at the start of March. That's assuming that all goes well. Unless, of course, I managed to get pregnant this cycle... yeah, right, like that could ever happen.

Current Mood: cynical cynical

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Comments
chenoameg From: chenoameg Date: January 10th, 2007 06:13 pm (UTC) (Link)
Off topic - I love that user picture.
psychohist From: psychohist Date: January 10th, 2007 07:37 pm (UTC) (Link)
To be slightly nitpicky, I'm not sure a fragmentation of A (<5%) is clearly better than B (5-25%). When the embryo gets to the blastocyst stage, you want some cytoplasm in the central vacuole. But yeah, we knew the chances on the 5Cfair were not good.
enugent From: enugent Date: January 10th, 2007 08:09 pm (UTC) (Link)
I look forward to the report tomorrow. I had figured out what the 5 and 7 meant and that the 5 didn't have a good shot, but I certainly didn't want to say anything about it. I'm sorry they didn't make it, and I hope you can tweak the meds next time to bludgeon your ovaries into submission.

I'm having the frustration of annoying responses to meds myself, now. The first battery of tests showed that my progesterone was low during my luteal period (mine was 8, and they like to see at least 15). So I've been taking progesterone this cycle. But now my temp has dropped, and it's pretty clear I'm not pregnant - but my period won't start. The progesterone seems to be suppressing it. I've stopped taking it (on the advice of the nurse at the fertility clinic), but I'm realizing that waiting for your period when you know you aren't pregnant is even more annoying than waiting for it when you think you might be.
greyautumnrain From: greyautumnrain Date: January 10th, 2007 08:24 pm (UTC) (Link)
I'm realizing that waiting for your period when you know you aren't pregnant is even more annoying than waiting for it when you think you might be.

It certainly is. I think I've even mentioned that before myself. On my IUIs it would often take 2-3 days after the negative for my period to show.

If you're in the Boston area anytime soon you are welcome to raid my stash of progesterone suppositories. I don't expect I'll be using anything weaker than progesterone in oil shots before the stuff expires.
From: (Anonymous) Date: January 10th, 2007 09:00 pm (UTC) (Link)
Prog. definitely stopped my period from coming, FWIW. I wish you luck next month!
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